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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOS
All Species:
8.18
Human Site:
Y10
Identified Species:
15
UniProt:
P00540
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00540
NP_005363.1
346
37820
Y10
S
P
L
A
L
R
P
Y
L
R
S
E
F
S
P
Chimpanzee
Pan troglodytes
XP_528144
346
37828
Y10
S
P
L
A
L
R
P
Y
L
R
S
E
F
S
P
Rhesus Macaque
Macaca mulatta
XP_001087400
305
33010
Dog
Lupus familis
XP_544088
372
41133
Y34
S
P
L
S
R
H
S
Y
L
P
S
E
F
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P00536
390
42872
R60
S
L
C
R
Y
L
P
R
E
L
S
P
S
V
D
Rat
Rattus norvegicus
P00539
339
37603
L11
P
L
I
L
C
R
Y
L
P
R
E
L
S
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P10741
349
38245
E14
F
N
S
F
L
P
L
E
L
S
P
S
A
D
L
Frog
Xenopus laevis
P12965
359
39143
F10
S
P
I
P
V
E
R
F
L
P
R
D
L
S
P
Zebra Danio
Brachydanio rerio
NP_991143
329
36509
R9
P
S
P
I
P
V
T
R
L
L
P
K
D
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1Y5
476
53320
R54
A
K
L
V
G
V
R
R
G
I
S
S
I
D
L
Sea Urchin
Strong. purpuratus
XP_789415
418
47752
A24
A
F
L
R
I
Y
Q
A
Y
L
Q
R
T
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130627
368
40934
S10
R
L
Q
C
F
K
K
S
S
G
G
G
N
G
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2MHE4
390
44263
R16
F
R
L
R
W
S
L
R
S
K
L
P
L
E
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85.5
78.4
N.A.
65.3
71
N.A.
N.A.
62.1
53.7
46.5
N.A.
N.A.
N.A.
20.1
26.3
Protein Similarity:
100
99.4
86.4
83.5
N.A.
71.7
78.9
N.A.
N.A.
72.7
66.5
62.1
N.A.
N.A.
N.A.
36.1
40.6
P-Site Identity:
100
100
0
66.6
N.A.
20
13.3
N.A.
N.A.
13.3
33.3
6.6
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
0
73.3
N.A.
20
20
N.A.
N.A.
13.3
60
13.3
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
29.6
N.A.
22.8
N.A.
N.A.
Protein Similarity:
N.A.
43.2
N.A.
42
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
16
0
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
8
16
8
% D
% Glu:
0
0
0
0
0
8
0
8
8
0
8
24
0
8
0
% E
% Phe:
16
8
0
8
8
0
0
8
0
0
0
0
24
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
8
8
8
8
0
8
16
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
8
8
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
8
8
0
0
8
0
8
0
8
0
% K
% Leu:
0
24
47
8
24
8
16
8
47
24
8
8
16
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
16
31
8
8
8
8
24
0
8
16
16
16
0
8
39
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
8
8
0
24
8
24
16
31
0
24
8
8
0
0
8
% R
% Ser:
39
8
8
8
0
8
8
8
16
8
39
16
16
31
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% T
% Val:
0
0
0
8
8
16
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
8
24
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _